Prostate Cancer and Bone Loss
نویسندگان
چکیده
منابع مشابه
Androgen-deprivation bone loss in patients with prostate cancer.
An increasing number of men with prostate cancer being treated with androgen-deprivation therapy (ADT) are at increased risk for developing osteoporosis. Osteoporosis often is overlooked in men and can have significant adverse economic effects and reduce quality of life, particularly if a fracture occurs. Nurses play a major role in identifying men who are at risk because of lifestyle factors a...
متن کاملCastration-induced bone loss triggers growth of disseminated prostate cancer cells in bone.
Up to 90% of patients with castrate-resistant prostate cancer develop bone metastases, and the majority of these men have received androgen deprivation therapy known to cause bone loss. Whether this treatment-induced change to the bone microenvironment affects disseminated tumour cells, potentially stimulating development of bone metastasis, remains to be determined. The objective of this study...
متن کاملCancer treatment-induced bone loss in patients with breast or prostate cancer.
PURPOSE/OBJECTIVES To review the prevalence, consequences, pathophysiology, diagnosis, and treatment of cancer treatment-induced bone loss (CTIBL) in patients with breast or prostate cancer. DATA SOURCES Published articles, abstracts, book chapters, electronic resources, and manufacturer information. DATA SYNTHESIS CTIBL is a long-term complication associated with cancer therapies that caus...
متن کاملAndrogen-deprivation therapy and bone loss in prostate cancer patients: a clinical review.
Androgen-deprivation therapy (ADT) has become a standard of care in the management of advanced prostate cancer or as an adjunct therapy. However, ADT is associated with a well-known deleterious effect on bone health, resulting in a decrease in bone-mass density (BMD) and increased risk for fracture. With the longer life expectancy of prostate cancer patients, improvement of the quality of life ...
متن کاملProstate Cancer and Bone: The Elective Affinities
The onset of metastases dramatically changes the prognosis of prostate cancer patients, determining increased morbidity and a drastic fall in survival expectancy. Bone is a common site of metastases in few types of cancer, and it represents the most frequent metastatic site in prostate cancer. Of note, the prevalence of tumor relapse to the bone appears to be increasing over the years, likely d...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2006
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem.91.4.9994